Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11176-1

A tetravalent nanobody-based myeloid-selective IL-10 receptor agonist recapitulates IL-10’s potent suppression of monocytes, macrophages and dendritic cells while avoiding stimulation of T cells.

Nature, Published online: 08 July 2026; doi:10.1038/s41586-026-10712-3

Viscoelastic phase separation is used to fabricate non-collapsible, air-rich networks in high-water-content hydrogels containing silica aerogel beads, allowing air to permeate through the material and enabling a tenfold increase in oxygen permeability over pristine hydrogels.

Nature, Published online: 10 June 2026; doi:10.1038/s41586-026-10613-5

Molecular glue degraders of the RNA-binding protein HuR have therapeutic potential for BRAF-mutant cancers.