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Efficient and precise programmable DNA knock-in without double-strand breaks

22 July 2026 at 01:00

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10819-7

Kilobase-scale nickase-targeting (KNIT) editing enables single-nick-based DNA insertion across genomic loci and cell types, supporting insertion of DNA fragments exceeding 10 kb, with high efficiency and minimal unwanted off-target effects.

Soft-chemistry routes to entropy-engineered nanomaterials: complexity-driven performance in redox electrocatalysis

Energy Environ. Sci., 2026, Advance Article
DOI: 10.1039/D6EE00987E, Review Article
Linwei Jiang, Cuifang Wang, Huaiyuan Kang, Zhiwen Lu, Hsien-Yi Hsu, Zongyou Yin, Mark A. Buntine, Zongping Shao, Zhenhai Wen, Guohua Jia
Soft-chemistry routes enable the tailored synthesis of entropy-engineered nanomaterials with tunable size, morphology, and unconventional phases, unlocking multielement synergy for efficient redox electrocatalysis.
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