Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10843-7

Integration of genome-scale CRISPR screening data from traditional cell lines and next-generation cancer models expands the representation of tumour subtypes and genomic alterations in The Cancer Dependency Map.

Nature, Published online: 05 August 2026; doi:10.1038/s41586-026-10806-y

The international collaboration of the Human Cancer Models Initiative presents a comprehensive resource of next-generation cancer models from 2,780 donors with 25 cancer types and integrated tumour–model genomic, transcriptomic and epigenomic analyses.