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Normal view

Structural basis of the RNA-editing cascade in trypanosome mitochondria

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10831-x

Cryo-electron microscopy sheds light on the architecture of the Trypanosoma brucei mitochondrial editosome and reveals how this assembly mediates mRNA editing through the insertion and deletion of uridine nucleotides.

Planetary-mass exosatellite detected around the substellar companion of a star

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10751-w

Radial velocity measurements provide evidence for a Jupiter-mass exosatellite orbiting the brown dwarf companion CD-35 2722 B, a promising detection of an exomoon-like object.

AI-redesigned starting points and outcomes enhance protein evolution

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10820-0

A workflow using artificial intelligence-redesigned starting points to evolve enzymes with improved properties compared with those evolved from natural proteins is established.

Brown bullhead catfish melanoma represents a novel transmissible cancer

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10828-6

Whole-genome sequencing analysis of tumour and matched non-tumour host tissues of the brown bullhead catfish reveals a type of naturally occurring transmissible cancer.

Mapping drivers of life expectancy change in Asia from 1990 to 2023

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10739-6

Using the Global Burden of Disease Study data across Asian countries and territories, life expectancy trends and the effects of cause-specific mortality and risk factors on changes in these trends are analysed.

Genetic background sets the trajectory of experimental cancer evolution

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10821-z

Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stages of cancer development.
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