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Received — 8 June 2026 ⏭ Nature

Nature
GPR15-guided CD8<sup>+</sup> T regulatory cells control intestinal inflammation 8 June 2026 at 01:00

GPR15-guided CD8<sup>+</sup> T regulatory cells control intestinal inflammation

Nature

By: Jing Cui · Zuojia Chen · Yan H. Cheng · Jia Nie · Maria H. Zhu · Chen Xiang · Samuel Chauvin · Wiem Lassoued · Can Liu · Kartika Padhan · Jian Song · Joy A. Pai · Borja Ocón · Yifan Yang · Yikun Yao · Ann Y. Park · Justin Q. Gabrielski · Lixin Zheng · Ping Du Jiang · Yu Zhang · Huie Jing · Leilei Xu · Vicky Chen · Brent A. Calabresi · Stefania Pittaluga · David E. Kleiner · Clifton L. Dalgard · Sinan Sari · Salim Can · Elif Karakoc-Aydiner · Safa Baris · Baran Erman · Michael Field · Jocelyn A. Silvester · Gwen Saccocia · Eman K. Buhamrah · Khaled Husain · Zahra Chavoshzadeh · Nima Rezaei · Ali İşlek · Hasan Baş · Fatma Dereli Devrez · Rafah Mackeh · Ivan J. Fuss · Daniel S. Reich · Shania Bailey · Houssein Abdul Sater · James L. Gulley · Juraj Kabat · Margery Smelkinson · Sundar Ganesan · Zhenghao Chen · Peter C. Grayson · Neelam Redekar · Justin Lack · Zhiyong Lu · Bernice Lo · Hassan Abolhassani · Ahmet Ozen · Athos Bousvaros · Scott B. Snapper · Eugene C. Butcher · Juan Ravell · Rémy Bosselut · Helen C. Su · Chuan Wu · Michael J. Lenardo

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/s41586-026-10749-4

GPR15-guided CD8⁺ T regulatory cells control intestinal inflammation

Nature
Distributed control circuits across a brain-and-cord connectome 8 June 2026 at 01:00

Distributed control circuits across a brain-and-cord connectome

Nature

By: Alexander S. Bates · Jasper S. Phelps · Minsu Kim · Helen H. Yang · Arie Matsliah · Zaki Ajabi · Eric Perlman · Kevin M. Delgado · Mohammed Abdal Monium Osman · Christopher K. Salmon · Jay Gager · Benjamin Silverman · Sophia Renauld · Farzaan Salman · Janki Patel · Matthew F. Collie · Jingxuan Fan · Diego A. Pacheco · Yunzhi Zhao · Wenyi Zhang · Laia Serratosa Capdevila · Ruairí J. V. Roberts · Eva J. Munnelly · Nina Griggs · Helen Langley · Borja Moya-Llamas · Zuoyu Zhang · Ryan T. Maloney · Szi-chieh Yu · Amy R. Sterling · Marissa Sorek · Krzysztof Kruk · Nikitas Serafetinidis · Serene Dhawan · Finja Klemm · Paul Brooks · Ellen Lesser · Jessica M. Jones · Sara E. Pierce-Lundgren · Su-Yee Lee · Yichen Luo · Andrew P. Cook · Theresa H. McKim · Dimitrios Stasi Giakoumas · Benjamin Gorko · Justin Ellis-Joyce · Jiayi Zhang · Emily C. Kophs · Tjalda Falt · Alexa M. Negron-Morales · Austin Burke · James Hebditch · Kyle P. Willie · Ryan Willie · Sergiy Popovych · Nico Kemnitz · Dodam Ih · Kisuk Lee · Ran Lu · Akhilesh Halageri · J. Alexander Bae · Ben Jourdan · Gregory Schw

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/s41586-026-10735-w

Distributed control circuits across a brain-and-cord connectome

Nature
Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding 8 June 2026 at 01:00

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding

Nature

By: Jingkun Zeng · Zhiyuan Cheng · Huadong Chen · Zhaojun Wang · Jared Thompson · Kadin T. Crosby · Hesong Han · Arushi Singhal · Wayne Ngo · Chenglong Xia · Daniel Rosas-Rivera · Zeyuan Zhang · Min Hyung Kang · Ying Mao · Morgan E. Diolaiti · Giselle C. Lee · John F. X. Diffley · Yixuan Song · Longhui Qiu · Nathan M. Krah · Niren Murthy · Ryan N. Jackson · Yang Liu · Alan Ashworth · Jennifer A. Doudna

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/s41586-026-10738-7

Targeting Cancer-Specific Mutations with RNA-Triggered Chromatin Shredding

Nature
Fifty years since a simple equation described the chaos of biology 8 June 2026 at 01:00

Fifty years since a simple equation described the chaos of biology

Nature

By: Michael P. H. Stumpf · Zoë Laidlaw

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/d41586-026-01584-8

An exploration of chaos theory in population dynamics showed that unpredictable systems can often be modelled using surprisingly simple mathematics.

Nature
How AI is reshaping discovery in maths and physics 8 June 2026 at 01:00

How AI is reshaping discovery in maths and physics

Nature

By: Mikhail Burtsev · Yang-Hui He · Evgeny Sobko · Ananyo Bhattacharya · Thore Graepel

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/d41586-026-01820-1

Artificial intelligence is not replacing human intuition in these fields, but reimagining how questions are asked, explored and understood.

Nature
Bots are scraping open data — how should researchers respond? 8 June 2026 at 01:00

Bots are scraping open data — how should researchers respond?

Nature

By: Chris Stokel-Walker

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/d41586-026-01689-0

The snowballing ability of artificial intelligence to trawl open data sets has some scientists worried about losing control of their information.

Nature
Nuclear-fusion firm says plant will deliver electricity to grid — but big questions remain 8 June 2026 at 01:00

Nuclear-fusion firm says plant will deliver electricity to grid — but big questions remain

Nature

By: Elizabeth Gibney

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/d41586-026-01795-z

Commonwealth Fusion Systems has published several papers detailing the design of its ARC fusion power plant.

Nature
Daily briefing: A spectacular flowery frame for the Milky Way 5 June 2026 at 01:00

Daily briefing: A spectacular flowery frame for the Milky Way

Nature

By: Flora Graham

5 June 2026 at 01:00

Nature, Published online: 05 June 2026; doi:10.1038/d41586-026-01837-6

Enjoy the month’s best science images. Plus, a smartphone’s selfie camera can monitor your heart rate and whether AI will drag astrophysics down to Earth.

Nature
Why are so many young people getting cancer? What researchers do and don’t know 8 June 2026 at 01:00

Why are so many young people getting cancer? What researchers do and don’t know

Nature

By: Heidi Ledford

8 June 2026 at 01:00

Nature, Published online: 08 June 2026; doi:10.1038/d41586-026-01780-6

Possible explanations for the trend are emerging, but are likely to vary from one type of tumour to another.