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Normal view

Received — 2 August 2026 ⏭ Nature
Received — 16 July 2026 ⏭ Nature

GPC3-specific dnTGFβRII-armoured CAR T cells for hepatocellular carcinoma

✇Nature
By: Qi Zhang · Qihan Fu · Yinan Shen · Wanyue Cao · Gaowei Jin · Yize Zhang · Jiangchao Wu · Cao Chen · Hongkan Wang · Xingyuan Xu · Ke Sun · Xing Xue · Attilio Bondanza · Daisy Cao · Nina Chu · Nick Durham · Mark Cobbold · Benedetto Farsaci · Maria Letizia Giardino Torchia · Yixin Hao · Yi Hong · Jiaqi Huang · Michael Humphries · Qijie Jian · Gordon Moody · John Stone · Lingyan Sun · Eric Tu · Fei Wang · Fuzhe Wang · Ye Yang · Yihong Yao · Andy Zou · Xueli Bai · Tingbo Liang
15 July 2026 at 01:00

Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10786-z

Chimeric antigen receptor (CAR) T cells for antitumour therapy ‘armoured’ with a dominant-negative TGFβ receptor II show enhanced efficacy and tolerable safety in patients with advanced hepatocellular carcinoma who have developed resistance or not responded to previous treatment.
Received — 24 June 2026 ⏭ Nature

Optical cooling by interfacial charge transfer in 2D heterostructures

✇Nature
By: Jiamin Lin · Baixu Xiang · Renguang Liu · Jinyang Ling · Gang Wang · Le Zhang · Li Li · Hua Li · Dongxu Zhang · Zhexing Duan · Qi Zhang · Changjin Wan · Wei Wang · Xingzhi Wang · Junhao Lin · Huajian Gao · Qihua Xiong · Weigao Xu
24 June 2026 at 01:00

Nature, Published online: 24 June 2026; doi:10.1038/s41586-026-10662-w

Optical cooling in two-dimensional semiconductor heterostructures is demonstrated through phonon-assisted interfacial charge transfer, enabling cryogen-free thermal management without stringent quantum-efficiency requirements.
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