Nature, Published online: 23 July 2026; doi:10.1038/d41586-026-02275-0
From intelligent ships to clues about eclipses, Homer’s The Odyssey reveals how Bronze Age Greeks understood the world.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10803-1
Chemotherapy, particularly with platinum-based drugs, is associated with substantial, rapidly detectable mutagenesis in childhood cancers, tripling private signatures and doubling mutation burden, highlighting therapy-induced tumour evolution and opportunities for safer, de-escalated treatment.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10831-x
Cryo-electron microscopy sheds light on the architecture of the Trypanosoma brucei mitochondrial editosome and reveals how this assembly mediates mRNA editing through the insertion and deletion of uridine nucleotides.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10751-w
Radial velocity measurements provide evidence for a Jupiter-mass exosatellite orbiting the brown dwarf companion CD-35 2722 B, a promising detection of an exomoon-like object.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10820-0
A workflow using artificial intelligence-redesigned starting points to evolve enzymes with improved properties compared with those evolved from natural proteins is established.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10828-6
Whole-genome sequencing analysis of tumour and matched non-tumour host tissues of the brown bullhead catfish reveals a type of naturally occurring transmissible cancer.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10739-6
Using the Global Burden of Disease Study data across Asian countries and territories, life expectancy trends and the effects of cause-specific mortality and risk factors on changes in these trends are analysed.Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10821-z
Experimentally replaying tumour evolution in divergent mouse strains reveals the importance of interactions between genetic ancestry and acquired cancer-driving mutations in shaping the earliest stages of cancer development.Nature, Published online: 20 July 2026; doi:10.1038/d41586-026-02231-y
Anticipating from the start the various ways a research programme can succeed or fail can avoid problems later. Here’s how to do it.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10897-7
Selectivity Emerges from Indiscriminate PhotoreductionNature, Published online: 15 July 2026; doi:10.1038/s41586-026-10789-w
In vivo ligation of clinically used therapeutic antibodies via bioorthogonal click chemistry to antibody–drug conjugates leads to enhanced antitumour activity in heterogeneous and treatment-resistant tumours.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10775-2
Scenario simulations using global economic models show that by 2050 the transformation of food systems towards healthy diets, improved productivity and halving of food waste result in a restructuring of global agriculture.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10801-3
A molten salt, high-pressure synthesis method enables solution-based production of diverse refractory metal nitride nanocrystals, expanding access to technologically important nitride materials for advanced applications.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10780-5
A Bayesian generative framework that integrates longitudinal electronic health records with genetic data to identify latent disease signatures is presented.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10743-w
A database of daily dust metals in Europe is established and a machine learning model shows that transported dust intrusion events over the past decade are linked to changes in atmospheric circulation, while an ice core shows that the increase in dust since pre-industrial times is governed by increasing aridity in North Africa..Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10722-1
Large-scale behavioural studies show that people approach a new game systematically and adaptively rationally. A cognitive model called the ‘Intuitive Gamer’ offers insights into this process and may inform the design of more flexible AI systems.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10793-0
Single-nucleus RNA-seq and ATAC-seq analyses on post-mortem brain samples from African American, Latin and white individuals identify cell-type-specific molecular signatures that are associated with cognitive impairment and/or Alzheimer’s disease across diverse population groups.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10779-y
A combination of different manipulations in mouse models of spontaneous intestinal adenoma formation dissects the roles of systemic and epithelial ketogenesis versus dietary lipids in ketogenic diet-mediated intestinal tumorigenesis, highlighting the need for nuanced consideration of dietary strategies for cancer prevention.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10781-4
An encyclopedia of more than 92 million enhancer–gene regulatory interactions created as part of the ENCODE4 project provides a valuable resource for future studies of gene regulation and human genetics.Nature, Published online: 15 July 2026; doi:10.1038/s41586-026-10786-z
Chimeric antigen receptor (CAR) T cells for antitumour therapy ‘armoured’ with a dominant-negative TGFβ receptor II show enhanced efficacy and tolerable safety in patients with advanced hepatocellular carcinoma who have developed resistance or not responded to previous treatment.
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