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Emergent decadal predictability in Antarctic contribution to sea-level rise

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10614-4

Although Antarctic ice loss projections diverge widely by 2100, this Perspective shows that present-day rates robustly predict mid-century sea level rise, providing a firm basis for near-term planning, while highlighting priorities for model development aimed at resolving longer-term sea level rise uncertainty.

A distant brown dwarf coplanar to a warm Jupiter and a hot super-Earth

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10586-5

Analysis of long-term radial velocity data and transit time variations, induced by a super-Earth, a warm Jupiter and a brown dwarf in a coplanar orbit around the relatively young star TOI201.

Probing picometre-scale interlayer deformations via hyperbolic polaritons

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10638-w

A new polaritonic optical method that uses the mid-infrared out-of-plane hyperbolic polaritons mode is described and experimentally validated to allow the examination of picometre-scale interlayer deformations, providing a bridge between nanomechanics and photonics.

Optical fibre gripper for high-performance 3D micromanipulation

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10673-7

A miniature three-dimensional optical fibre gripper enables powerful, precise micromanipulation of particles and single cells in confined spaces, bridging the gap between optical and mechanical tweezers.

A prototype differential atom interferometer for fundamental physics

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10617-1

A prototype differential atom interferometer operates at the standard quantum limit with no excess noise beyond atom shot noise, achieving performance in line with the specifications for future long-baseline atom interferometers.

Structure of the pre-initiation complex explains CMGE biogenesis

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10657-7

Cryo-electron microscopy and biochemical reconstitution experiments in yeast provide insight into the assembly of the CMGE complex, a helicase that establishes bidirectional DNA replication in eukaryotic cells, and elucidate the role of the firing factor Sld2.

A 98-qubit trapped-ion quantum computer with all-to-all connectivity

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10676-4

A new quantum computer, Quantinuum Helios, which is a 98-qubit trapped-ion quantum processor built on the QCCD architecture, demonstrates performance well beyond classical capabilities and provides a path for scaling up quantum computing.

Fast formation to reinforce lithium-rich cathodes

Nature, Published online: 17 June 2026; doi:10.1038/s41586-025-09553-3

Fast formation in lithium-ion batteries outperforms conventional slow formation, lowering costs and improving battery capacity, stability and cycle life, offering broader application to electrode systems.

Revealing competitive interfacial reactions in high-energy Li–S batteries

Nature, Published online: 17 June 2026; doi:10.1038/s41586-025-09473-2

Visualization of concentration-driven phase segregation within high-concentration interfacial layers in the context of high-energy lithium–sulfur batteries using liquid-cell electrochemical transmission electron microscopy reveals competitive interfacial reactions under lean electrolyte conditions at different phase boundaries.

Molecular basis of polyadenylated RNA fate determination in the nucleus

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10650-0

Biochemical, structural and cell biological analyses reveal that UAP56 (DDX39B) assembles with a TREX-2–like module that redirects non-functional polyadenylated RNAs from export to degradation.

Rock weathering can counteract river CO<sub>2</sub> emissions induced by permafrost thaw

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10664-8

Permafrost thaw on the Qinghai–Tibet Plateau increases rock-weathering rates while reducing river CO2 emissions, suggesting geological carbon fluxes may eventually outpace thaw-driven emissions.

Cortical development dynamics across autism spectrum disorder mouse models

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10679-1

Using single-nucleus multi-omic sequencing, diverse autism spectrum disorder-linked gene mutations converge on transient, stage-specific disruptions in early brain development, and highlight sex-specific gene expression alterations.

Confined migration induces non-lethal DNA damage in developing neurons

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10648-8

The migration of neurons in developing cerebral and cerebellar cortices is accompanied by massive DNA double-strand breaks due to mechanostress during passage through narrow interstitial spaces.

Analysis of 173,303 exomes and genomes in the Pakistan Genome Resource

Nature, Published online: 17 June 2026; doi:10.1038/s41586-026-10667-5

The Pakistan Genome Resource compiles biobank data from 173,303 individuals with high familial relatedness, broadening the catalogue of human genetic variation and establishing a population-specific genomic reference for Pakistan.
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