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Received — 25 July 2026 ⏭ Nature

Precise DNA base editing using AlphaFold3-based contact modelling

✇Nature
By: Haowei Meng · Zhixin Lei · Yongchang Yan · Liren Wang · Sihan Zhang · Xichen Rao · Chuyun Shao · Xiaoting Zhang · Ke Chen · Lei Yang · Rongrong Liu · Gaohui Yang · Ruoyu Shen · Ruichu Gu · Xinyan Wang · Yiya Wang · Suiru Lu · Zhicong Lv · Bo He · Han Wen · Dali Li · Chengqi Yi
22 July 2026 at 01:00

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10794-z

ContactSeek is an AlphaFold3-driven model that can improve the precision of genome-editing tools.
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