❌

Normal view

GRP75-dependent SIMPA mediates inter-organellar quality control

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-10733-y

Proteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, enabling selective clearance of damaged proteins and preserving mitochondrial integrity.

Clasping folds enable superior elastic strength of graphene films

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11109-y

Two-dimensional graphene films with unusual folded surfaces are synthesized through a modular assembly strategy and show enhanced strength, toughness and elastic strain owing to stress distribution between interlayer folds.

Isomeric multi-hydrogen-bonding enables blue perovskite LEDs

Nature, Published online: 01 July 2026; doi:10.1038/s41586-026-10723-0

Hydrogen-bonding networks engineered with isomeric molecules enable stable, saturated blue perovskite LEDs with record external quantum efficiencies up to 22.0%, advancing high-performance full-colour display technologies.

Plastoglobules compartmentalize nitrogen assimilation in maize

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10610-8

Chloroplast plastoglobules act as nitrogen-assimilation hubs in maize, with key enzymes enhancing nitrogen-use efficiency and offering new strategies for developing high-yield, sustainable crops.

Spermine is an endogenous iron chelator that inhibits ferroptosis

Nature, Published online: 03 June 2026; doi:10.1038/s41586-026-10597-2

A non-canonical metabolic route for spermine synthesis mediated by ALDH18A1 limits iron availability and lipid peroxidation in hepatocellular carcinoma.
❌