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Normal view

Sequential reading of a stepwise-shortened peptide immobilized on nanopore

Nature, Published online: 29 July 2026; doi:10.1038/s41586-026-10881-1

A nanopore-based ‘chop and measure’ method sequences peptides at single-amino-acid resolution by using enzymatic digestion to progressively shorten the N terminus one residue at a time, together with repetitive N-terminus re-reading.

Semiconducting and magnetic lanthanide MXenes from intercalated halides

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10802-2

A bottom-up synthesis strategy creates lanthanide MXenes (Ln2CT2) that combine semiconducting behaviour with ferromagnetism, offering a promising new class of two-dimensional materials for spintronic applications.

Efficient and precise programmable DNA knock-in without double-strand breaks

Nature, Published online: 22 July 2026; doi:10.1038/s41586-026-10819-7

Kilobase-scale nickase-targeting (KNIT) editing enables single-nick-based DNA insertion across genomic loci and cell types, supporting insertion of DNA fragments exceeding 10 kb, with high efficiency and minimal unwanted off-target effects.
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