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Early studies hint that ketones may affect pathways linked to PTSD

11 September 2026 at 05:12
An integrative review found that ketogenic therapy may influence metabolic, inflammatory, oxidative stress, and neurotransmitter pathways implicated in PTSD, with animal studies and small human studies reporting early signs of symptom improvement. Human evidence remains limited to very small cohorts, case reports, and pilot studies, and controlled trials have yet to establish clinical efficacy.

Early studies hint that ketones may affect pathways linked to PTSD

People with ADHD face higher odds of gastrointestinal problems

11 September 2026 at 04:20
University of Warwick researchers have analyzed data from over 1.9 million people across 23 studies and found that ADHD is linked to an almost 50% increase in overall gastrointestinal symptoms compared with people without ADHD The association was even stronger for specific problems: nearly double the odds of constipation, a 58% increase in irritable bowel syndrome, and more than four times the odds of encopresis (loss of bowel control).

People with ADHD face higher odds of gastrointestinal problems

Laser therapy offers new hope for inoperable pancreatic tumors

11 September 2026 at 04:01
UCI Health, the clinical enterprise of the University of California, Irvine, is conducting a first-in-human, phase 1 clinical trial using laser light to target localized but inoperable pancreatic tumors to help patients become cancer free.

Laser therapy offers new hope for inoperable pancreatic tumors

Coffee after colorectal cancer? Decaf and caffeine show different links with mortality

11 September 2026 at 03:58
In a prospective analysis of 1,098 people with colorectal cancer, researchers found no significant association between total or caffeinated coffee intake and all-cause or colorectal cancer-specific mortality in the cohort overall. Decaffeinated coffee was associated with lower all-cause mortality, while the highest quartile of caffeine intake was associated with lower all-cause and colorectal cancer-specific mortality, although the observational study cannot establish causation.

Coffee after colorectal cancer? Decaf and caffeine show different links with mortality

Healthy checkout ordinance linked to lower soda and candy sales

11 September 2026 at 03:51
A new study found that a healthy checkout ordinance implemented in Berkeley, Calif. supermarkets, drug stores, and mass-market retailers in 2021 was linked to notable decreases in soda sales overall and small-package candy in supermarkets, but greater enforcement of such policies is essential for sustained and meaningful public health benefit.

Healthy checkout ordinance linked to lower soda and candy sales

New treatment approach preserves organs, improves survival in head and neck cancer patients

10 September 2026 at 13:53
Patients with locally advanced head and neck squamous cell carcinoma (HNSCC) whose tumors responded to neoadjuvant immunochemotherapy (ICT) and who underwent less extensive surgery had high disease-free survival and organ preservation rates.

New treatment approach preserves organs, improves survival in head and neck cancer patients

New AI tool predicts breast cancer risk using repeated 3D mammograms

10 September 2026 at 13:18
An artificial intelligence model that analyzes women's past and recent annual 3D mammograms is more effective at predicting five-year risk of developing breast cancer than a tool that uses only the most recent, single 3D mammogram, as well as an AI model that analyzes 2D mammograms, a new study shows.

New AI tool predicts breast cancer risk using repeated 3D mammograms

Symptomless liver condition linked to heart and kidney disease

10 September 2026 at 12:49
A common liver condition thought to be harmless could be dramatically increasing the risk of heart disease, kidney failure and premature death, according to a new review led by University of Manchester and Northern Care Alliance NHS Foundation Trust researchers.

Symptomless liver condition linked to heart and kidney disease

Generative AI-driven drug Rentosertib enters Phase III trial for idiopathic pulmonary fibrosis

10 September 2026 at 08:35
Insilico Medicine, a clinical-stage biotechnology company powered by generative AI, today announced that it has dosed the first patient with Rentosertib (known as ISM001-055 / INS018_055) in GENESIS-IPF-3, a Phase III clinical trial (NCT07687459, CTR20262475) at Peking Union Medical College Hospital, while Shanghai Pulmonary Hospital has also enrolled its first patient on the same day.

Generative AI-driven drug Rentosertib enters Phase III trial for idiopathic pulmonary fibrosis

Nighttime light exposure may alter heart structure and function

10 September 2026 at 08:16
Exposure to light during the nighttime is linked to important and potentially harmful changes to the structure and function of the heart, according to a study of more than 11,000 people published in the European Heart Journal today (Thursday).

Nighttime light exposure may alter heart structure and function

Tizanidine looked promising early in a migraine trial, but the benefit did not last

10 September 2026 at 05:44
A randomized, double-blind, placebo-controlled trial found that low-dose tizanidine did not provide sustained reductions in headache burden over 12 weeks in people with episodic migraine, despite a transient improvement with the 1 mg dose at week 4. Exploratory analyses suggested that smoking and sex may influence tizanidine exposure, while sex-specific efficacy signals remained hypothesis-generating and require confirmation.

Tizanidine looked promising early in a migraine trial, but the benefit did not last

Rentosertib shifts multiple proteomic aging clocks toward younger age profiles in IPF trial

10 September 2026 at 05:24
Researchers applied six proteomic aging clocks to serum samples from a phase 2a trial of rentosertib in people with idiopathic pulmonary fibrosis and found treatment-associated shifts toward younger predicted biological-age profiles, particularly with the 30 mg twice-daily regimen. Additional proteomic analyses linked treatment to changes in senescence, metabolism, growth-factor signaling, and fibrosis-related pathways, although the study could not determine whether these effects reflected genuine geroprotection rather than disease modification.

Rentosertib shifts multiple proteomic aging clocks toward younger age profiles in IPF trial
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