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Expansion and CAR engineering of granulocyte-monocyte progenitors for cellular immunotherapy

9 September 2026 at 18:25

Publication date: 20 August 2026

Source: Cell, Volume 189, Issue 17

Author(s): Shi Yue, Zheng Guo, Crystal Pan, Xueyuan A. Jing, Litao Tao, Tai Nguyen, Jiaqi Tang, Yanpui Chan, Humberto Contreras-Trujillo, Du Jiang, Xue Yan, Hang Xiang, Xugeng Liu, Celia Bloom, Asiri Ediriwickrema, Sebastian Koschade, Xiao Wang, Ziyuan Wang, Natalie Shu, Yingxiao Shi

A CRISPR knockout mouse library for functional genomics in influenza research

16 July 2026 at 14:42

Publication date: 9 July 2026

Source: Cell, Volume 189, Issue 14

Author(s): Hiroshi Ueki, Yuriko Tomita, Calvin Duong, Hiromichi Mitake, Maki Kiso, Yuri Furusawa, Dongming Zhao, Tiago Jose da Silva Lopes, Li Wu, Huapeng Feng, Seiya Yamayoshi, Satoshi Fukuyama, Makoto Yamashita, Manabu Ozawa, Masahito Ikawa, Nobuaki Yoshida, Tokiko Watanabe, Yoshihiro Kawaoka

Cellular architecture and neighborhood-informed virtual spatial tumor profiling from histopathology

16 July 2026 at 14:42

Publication date: 9 July 2026

Source: Cell, Volume 189, Issue 14

Author(s): Yuchen Li, Zhe Li, Ryan Quinton, Yuanfeng Ji, Xiaoming Zhang, Jinxi Xiang, Xiyue Wang, Sen Yang, Feyisope Eweje, Yijiang Chen, Xiangde Luo, Yuanyuan Li, Jonathan Mulholland, Siwei Chen, Colin Bergstrom, Ted Kim, Francesca Maria Olguin, Sierra Willens, Steven H. Lin, Jeffrey J. Nirschl

The critical role of the endogenous immune compartment after CAR T cell therapy in recurrent GBM

9 September 2026 at 18:25

Publication date: 20 August 2026

Source: Cell, Volume 189, Issue 17

Author(s): Nelson F. Freeburg, Daniel Chafamo, Gayathri Konanur Gopikrishna, Regan M. Murphy, Jacqueline J. Peng, Shridhar Parthasarathy, Sydney Dumont, Edward G. Estrada, Meghan T. Logun, Yusha Sun, Xin Wang, Payal Grover, Jesse L. Rodriguez, Daniel L. Zhang, Kristen Park, Yao Fu, Nadine Ben Hamouda, Isaias Hernandez-Verdin, Lamia Lamrani, Kelly A. Hicks

Global genetic interaction network of a human cell maps conserved principles and informs functional interpretation of gene co-essentiality profiles

12 June 2026 at 17:01

Publication date: 11 June 2026

Source: Cell, Volume 189, Issue 12

Author(s): Maximilian Billmann, Michael Costanzo, Xiang Zhang, Arshia Z. Hassan, Mahfuzur Rahman, Kevin R. Brown, Katherine S. Chan, Amy Hin Yan Tong, Carles Pons, Henry N. Ward, Catherine Ross, Jolanda van Leeuwen, Michael Aregger, Keith A. Lawson, Barbara Mair, Amy F. Roth, Nesli E. Sen, Duncan T. Forster, Guihong Tan, Patricia Mero

Somatic cancer variants enriched in Alzheimer’s disease microglia-like cells drive inflammatory and proliferative states

12 June 2026 at 17:01

Publication date: 11 June 2026

Source: Cell, Volume 189, Issue 12

Author(s): August Yue Huang, Zinan Zhou, Maya Talukdar, Liz Enyenihi, Michael B. Miller, Brian Chhouk, Ila Rosen, Mengyue Zheng, Minye Zhou, Averill Yang, Edward Stronge, Madel Durens, Minh Nguyen, Jaejoon Choi, Boxun Zhao, Sattar Khoshkhoo, Junho Kim, Rebecca Andersen, Zheming An, Yuchen Cheng

A 3D morphogenetic blueprint for metastatic outgrowth in breast cancer

12 June 2026 at 17:01

Publication date: 11 June 2026

Source: Cell, Volume 189, Issue 12

Author(s): Robin Caire, Roberta Bordo, Francesca Zanconato, Tito Panciera, Estelle Audoux, Paolo Contessotto, Michaela Fakiola, Ramona Bason, Oriana Romano, Ambela Suli, Giusy Battilana, Matteo Marchionni, Mattia Forcato, Sara Donzelli, Maria Vittoria Dieci, Gaia Griguolo, Mariantonia Carosi, Matteo Fassan, Vincenza Guzzardo, Angelo Paolo Dei Tos

Sulfur partitioning from cysteine controls T cell proliferation and effector function

12 June 2026 at 17:01

Publication date: 11 June 2026

Source: Cell, Volume 189, Issue 12

Author(s): Beth Kelly, Minsun Cha, Tatjana Gremelspacher, Jacob L. Martin, Massimo Andreis, Isha Maloo, Gustavo E. Carrizo, Mia Gidley, Michal A. Stanczak, Petya Apostolova, Joseph Longo, Lisa M. DeCamp, Eric H. Ma, Ryan D. Sheldon, Russell G. Jones, David E. Sanin, Ananya Majumdar, Erika L. Pearce

Systematic discovery of pro- and anti-HIV host factors in primary human CD4+ T cells

12 June 2026 at 17:01

Publication date: 11 June 2026

Source: Cell, Volume 189, Issue 12

Author(s): Ujjwal Rathore, Eli Dugan, Hunter Thornton, Vigneshwari Easwar Kumar, Rama Dajani, Ryan C. Burdick, Janet M. Young, Zachary Steinhart, Reanna Lao, Krista A. Delviks-Frankenberry, Wooyoung Choi, William S. Henriques, Ignacia Echeverria, Emma Dann, Ishaan Dureja, Nandini Pathak, Maya M. Arce, Justin McKetney, Jennifer M. Umhoefer, Simrun Parulekar

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