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GRP75-dependent SIMPA mediates inter-organellar quality control

21 October 2026 at 01:00

Nature, Published online: 21 October 2026; doi:10.1038/s41586-026-10733-y

Proteotoxic stress drives formation of GRP75-dependent protein aggregates that signal through mitochondria–ER contact sites to activate targeted quality-control pathways, enabling selective clearance of damaged proteins and preserving mitochondrial integrity.

Advancing subseasonal forecasting with machine learning

Nature, Published online: 14 October 2026; doi:10.1038/s41586-026-11126-x

The AI framework probabilistic bias correction is shown to correct weather forecast errors 2 to 6 weeks ahead and boost forecast skill, making it promising for improved extreme-weather prediction.

High-performance LiFePO4 regeneration through Na-induced lattice activation and conductivity rewiring

28 May 2026 at 00:00

Energy Environ. Sci., 2026, Advance Article
DOI: 10.1039/D6EE02323A, Paper
Jiale Zhang, Shaofeng Li, Yan Yan, Jiexiang Li, Zeyu Dong, Peng Ge, Yue Yang, Jie Zeng
The recycling of spent LiFePO4 (LFP) is crucial for the sustainable development of Li-ion batteries.
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